Sildenafil, the active ingredient in Viagra, is one of several ED pills that’s considered a PDE5 inhibitor. When this enzyme is inhibited, it maximizes the effect of nitric oxide in your body. (That’s important, because your body naturally releases this gas when you’re sexually aroused. So it’s key to the process of getting and maintaining an erection.)
With more nitric oxide in play, the muscles around your penis can relax. In turn, blood flow to your penis improves. And it becomes easier to hold onto your erection, so you can enjoy a sexual encounter.
Sildenafil also works quickly. You can take our chewable Sildenafil tablets—only available on bluechew.com—about one hour before sex. Avoid taking food with your ED pills, especially fatty meals, since they can impact your body’s ability to absorb the drug.
When taken according to directions, the medication is fast-acting, reaching its peak concentration in your bloodstream about one hour after dosing. Then, the medication stays in your body for up to six hours, so you can enjoy a great night with that special someone.
How do I take this medication?Take this medication by mouth as directed and with a full glass of water, with or without food. If you are taking nitrates (e.g., nitroglycerin, isosorbide, nitrous oxide), do not take a nitroglycerin tablet within 24 hours of dosing, as this could result in a severe drop in blood pressure. Isosorbide mononitrate tablets are taken at dosages different from that listed above, so you may be prescribed with higher dosages of nitroglycerin than you would a low-nitroglycerin tablet with no tablet.
The maximum recommended dose of Sildenafil for Viagra is one tablet per day, not more than once per day. A dose of one tablet per day is unlikely to improve your blood pressure, but it can reduce your chances for heart attack and stroke.
Do not take Sildenafil if you are also using a alpha-blocker (e.g., doxazosin, tamsulosin) or heart-modifying antifungal (e.g., ketoconazole, itraconazole) since these medications can interact with Sildenafil. In addition, Sildenafil can also be used to treat pulmonary hypertension, which is a condition that causes high blood pressure in the lungs (pulmonary hypertension can cause shortness of breath, angina, or pain in the chest). If you have this condition, be sure to use a treatment plan that covers all medications and alpha-blockers (e.g., doxazosin, tamsulosin) while taking this medication.
If you are taking sildenafil along with any of the following medications or alpha-blockers:
Sildenafil can increase your blood pressure, so you should be aware of this risk and not alarmed by your Viagra prescriptions with it. If you become dizzy or experience any side effects, see your healthcare provider immediately. They may suggest stopping your Viagra treatment and talking to your doctor about other treatment options for you.
If you are taking sildenafil with:
, you should discuss your conditions and take the appropriate steps to mitigate your possible Sildenafil positive. They can help you avoid unwanted side effects and safely prescribed medications with Sildenafil.
You should discuss your concerns with your healthcare provider before starting Sildenafil treatment, so you can discuss other options for you. Your doctor will consider any factors that may affect how you should use Sildenafil, and they can prescribe other ED medications or alpha-blockers to help you manage your condition safely and effectively.
A new study has led to a potential for the treatment of erectile dysfunction (ED) among men in the UK.
The researchers published in the Journal of the American College of Cardiology in December 2013.
They looked at data from a large study that was led by Drs. William A. Pritchard of the University of Texas Southwestern Medical Center, and John D. Fugh of the University of Texas Southwestern Medical Center.
They examined data from the National Health and Nutrition Examination Survey of adults aged 40 to 69 years in the United States from 2004 to 2011. They examined data from 1,500 men who were followed up for 18 years with an estimated 4.5 million missing information. This was a representative sample of men who were taking a single drug called sildenafil, a similar drug to Pfizer's Viagra, which was used to treat erectile dysfunction.
They found that nearly half of the men with erectile dysfunction reported their ED symptoms as a result of taking the drug.
About one-third of the men did not have any ED symptoms, and the remaining men had no ED symptoms.
A total of 942 men were recruited from the general population in the United States. They filled out an online questionnaire which was administered to them and asked if they had any of the following:
During the follow-up, the researchers found that the average age of the men taking the drug was 51.5 years (range 25-63). They found that the average age of the men with erectile dysfunction was 59 years (range 30-76).
The men who had ED symptoms had an average of 2.5 times the risk of being hospitalized for a heart attack or stroke. The risk of being hospitalized for a heart attack or stroke was 2.5 times that of the general population.
Dr. Pritchard said the study was conducted to examine whether men who took the drug were more likely to develop ED than those who were not taking it.
He noted that the study has a number of limitations:
The study was not designed to be studied in a clinical setting and therefore, it was not a controlled trial.
Pritchard said that it is important to keep in mind that the researchers are not directly treating erectile dysfunction. They are simply trying to determine whether sildenafil is a suitable treatment for ED, based on the results of a study that they conducted in the 1990s.
He said that the study did have some limitations:
Pritchard said that the study was designed to be conducted to provide a baseline for treatment in men with erectile dysfunction.
He also said that it was important to know that the results of the study are not generalizable to the general population. It may have more to do with general health than research.
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